HORDB

ID: hor001093
Uniprot ID: O97371
Protein name: RFamide
Gene name: NA
Organism: Lymnaea stagnalis (Great pond snail) (Helix stagnalis)
Family: FMRFamide related peptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Lymnaea (genus), Lymnaeidae (family), Lymnaeoidea (superfamily), Hygrophila, Panpulmonata, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: TPHWRPQGRF
Length: 10(24-33)
Propeptide: MKTSQIMISTCCVLSVIFSLCYATPHWRPQGRFGKRTTEDDNVPDFGISRLQDIPIELMFSKNELSRRNSKPRLCSTSGVVDTRPAMHKSMRCK
Signal peptide: MKTSQIMISTCCVLSVIFSLCYA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001093_AF2.pdb

hor001093_ESM.pdb

Mass:	144214	Formula:	C59H84N20O13
Absent amino acids:	ACDEIKLMNSVY	Common amino acids:	PR
pI:	12.5	Basic residues:	3
Polar residues:	2	Hydrophobic residues:	2
Hydrophobicity:	-181	Boman Index:	-3636
Half-Life:	7.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	4464	Extinction Coefficient cystines:	5500
Absorbance 280nm:	611.11

PubMed ID: 9822740
Title: The Lymnaea Cardioexcitatory Peptide (LyCEP) Receptor: A G-protein-coupled Receptor for a Novel Member of the RFamide Neuropeptide Family